Endogenous suppression of WNT signalling in human embryonic stem cells leads to low differentiation propensity towards definitive endoderm
Dziedzicka et al. 2020, BioRxiv
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MSH2 knock-down shows CTG repeat stability and concomitant upstream demethylation at the DMPK locus in myotonic dystrophy type 1 human embryonic stem cells
Franck et al. 2021, Hum Mol Genet.
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Initiation of a conserved trophectoderm program in human, cow and mouse embryos
Gerri et al. 2020, Nature
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Pluripotent Stem Cells for Regenerative Medicine
Special Issue Editor of Cells: Prof. Dr. Claudia Spits
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Sustained intrinsic WNT and BMP4 activation impairs hESC differentiation to definitive endoderm and drives the cells towards extra-embryonic mesoderm
Markouli and Couvreu De Deckersberg et al. 2021, Scientific Reports
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High-throughput micropatterning platform reveals Nodal-dependent bisection of peri-gastrulation–associated versus preneurulation-associated fate patterning
Tewary and Dziedzicka et al. 2019, PLOS Biology
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Uncovering low-level mosaicism in human embryonic stem cells using high throughput single cell shallow sequencing
Keller et al. 2019, Scientific Reports
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Detection of Heteroplasmic Variants in the Mitochondrial Genome through Massive Parallel Sequencing
Mertens and Zambelli et al. 2019, Bio-protocol
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Gain of 20q11.21 in Human Pluripotent Stem Cells Impairs TGF-β-Dependent Neuroectodermal Commitment
Markouli et al. 2019, Stem Cell Reports
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